The Relationship between Mutation Types & Phenotypic Outcomes
Mutations can be defined as changes to the genome of an organism that lead to a wide range of phenotypic results. To identify the type, you can use the relationships among different alleles (m, l, and deletion) as well as the effect on the phenotypic outcomes of each genotype. An example of this is a + allele which can be indicative of a point mutation. A m allele, on the other hand, can signify a frameshift mutant. A deletion allele can indicate a deletion, or null mutation. Point mutations are when one base pair in the genetic code is altered, which results in an amino acid change in the encoded proteins. These can cause altered gene expression or a different phenotype. Frameshift mutations are when one nucleotide from the DNA sequence is deleted or added to another. It can cause an error in the reading of the DNA sequence and lead to the formation a nonfunctional protein. This could also result in a different phenotype. (Gardner and Hall 2020). A null mutation, or deletion of DNA, is when part of the genome is deleted. This can lead to a nullphenotype. Cont….