Is it possible to perform DNA profiling with SNPs instead of SSRs as DNA markers?

You can perform DNA profiling using SNPs rather than SSRs.

A DNA profile is an analysis that reveals genetic information about someone. DNA profiling is used for forensic purposes to locate criminal suspects and medical diagnostics to treat genetic disorders. SSRs, or Short Sequence Repeats, were previously used for DNA profiling. But, SNPs, which are single nucleotide polymorphisms, have recently become more prevalent as markers. For several reasons, SNPs outperform SSRs. SNPs are more abundant than SSRs and have a higher degree of polymorphism, meaning they have more variation between individuals (Schlötterer 2018). SNPs are more transferable among species and have a lower rate of mutation (Gauci, et al. 2020). They are therefore more reliable in DNA profiling and easier to be used with a range of species.
You can use SNPs for a range of DNA profiling methods, including single-strand conformational or restriction fragment length polymorphismsm (RFLP), single strand conformational (SSCP), and polymerase chains reaction (PCR). These are far more effective and economical than the ones used with SSRs, according to Xu 2018). SNPs are easier to analyze, so DNA profiling is possible with smaller samples. (Rost, et al. 2021).

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