Sign in
5′-GCATGCGTCG-3 ‘The Complementary Strand of DNA
Four nitrogenous bases make up the DNA primary sequence: adenine, cytosine and guanine. These bases make up complementary base pairs A-T and C-G. Each strand of DNA is composed of two distinct strands. A single DNA strand’s sequence reads: 5′-CGATCGCAGC-3″. Sequence of complementary strand 5”-GCATGCGTCG-3’. Watson and Crick first suggested that DNA’s two strands were complementary in 1953. This has been further supported by modern research, with a study published in 2016 showing how the Watson–Crick model of DNA is still valid today (Hou et al., 2016). These studies showed that both strands of DNA form complementary base pairs. The structure of DNA was also maintained. According to Xu et.al. (2016), the DNA sequence of one strand has a 5′-CGATCGCAGC-3 whereas the sequence sequence of its complementary strand is a 3′-GCTAGCGTAC-5. Zhao et.al., 2021. Based on the principle that complementary base pairs are in DNA, this means that adenine and thymine always pair with each other (Xu et al., 2016; Zhao et al., 2021). This means that the complementary sequence is exactly the opposite of the original but has the correct base pairing substituted in. To illustrate, the first base of the original strand (cytosine) is removed and replaced by the complementary amino acid (G). So, the sequence for the complement strand is 3’-GCTAGCGTAC-5’. Cont….
