The Use of CRISPR-Cas9 System within the Morrison Lab
The Morrison lab on the College of Chicago has been using the CRISPR-Cas9 system to review gene operate and develop new therapies for genetic illnesses. The CRISPR-Cas9 system is a gene enhancing instrument that permits for exact and environment friendly manipulation of genes in all kinds of organisms. This expertise was first developed in 2012 and has since been utilized in quite a few analysis labs, together with the Morrison Lab. The CRISPR-Cas9 system works by introducing a selected information RNA (gRNA) sequence right into a cell that binds to a goal gene. As soon as certain, the Cas9 enzyme cuts the DNA on the goal web site, permitting researchers to make exact and environment friendly modifications to the gene. The Morrison lab has used this technique to review the operate of genes associated to most cancers, Huntington’s illness, and different genetic problems (Florell et al., 2016; Li et al., 2021). The Morrison lab has additionally used the CRISPR-Cas9 system to develop gene remedy therapies for genetic illnesses. Through the use of this expertise, they’ve been in a position to introduce wholesome copies of genes into cells, permitting them to right genetic mutations that trigger illnesses. This method has been profitable in treating a wide range of genetic problems, together with cystic fibrosis, hemophilia, and Duchenne muscular dystrophy (Joyner et al., 2019; Galla et al., 2020). Cont….