Amino Acids’ Role in the Interaction of Epinephrine with its Receptor
Interaction between epinephrine receptor and receptor is complex biological process, which is crucial for many physiological functions. These interactions are facilitated through the formation hydrogen bonds and electrostatic interactions among various amino acids present on the receptor and the epinephrine. The amino acids identified by research are lysine (Dong and colleagues, 2016; Buxton and colleagues, 2020). Lysine, an essential amino acid for maintaining the interaction of epinephrine with its receptor, is important. Side chains of lysine are hydrogen-bonded capable and may contribute to strong electrostatic interactions. (Abbas, et al. 2020). Argonine, on the other hand is an positively charged amino acid which forms electrostatic interactions (Abbas et al. 2020). Two acidic amino acids such as glutamic and aspartic can form electrostatic interactions in epinephrine’s presence (Barrera Oro, 2021). Tyrosine, an amino acid with a high hydrophobicity that stabilizes the interaction of epinephrine to its receptor, is also important. The successful interaction of epinephrine with its receptor is dependent on the functioning amino acids, such as lysine and arginine. For stabilizing the interaction, and to ensure that physiological processes are properly regulated, both hydrogen bonds as well as electrostatic interactions are essential.