Determine structure of poly gene in D. melanogaster. Identifying the Structure of the Poly Gene in Drosophila melanogaster

Identification of the Structure and Functions of the Poly Gene in Drosophila Melanogaster 

Drosophila’s poly gene can be found on the third chromosome. It is large and responsible for the synthesizing of enzyme polyphenoloxidase (PPO). PPO is vital for melanin synthesis and formation of eggsshells in the fly’s development. The structure of the Poly gene is crucially important. Research has been conducted to identify the structure of the poly gene in order to gain a better understanding of its role in the fly’s development. Research has shown that the poly genome is made up of four exons plus three introns. The length of the first exon measures approximately 3.3kb, and those of the three other exons are approximately 1.2kb to 22.2kb. These introns range from approximately 11.5 kb up to 13.7kb. First intron, which is longest, contains many regulatory elements. These regulate the expression of the genes. Wang et al., 2002). The second intron includes a crucial region for regulation of transcription. The shortest and most important intron, the third, contains the region necessary for translation regulation. Cont….