Can you explain to me the discovery of TAQ Polymerase and its use in PCR?

The Discovery of Taq Polymerase and its Use in PCR

The invention of Taq Polymerase, a heat-resistant enzyme, was made in 1976 on the Cetus Company by Kary Mullis (Rabilloud, 2017). Taq Polymerase is derived from a micro organism, Thermus aquaticus, present in sizzling springs close to the Yellowstone Nationwide Park (Ellington & McPherson, 2016). This discovery revolutionized the sphere of molecular biology, because the enzyme had the power to face up to excessive temperatures and facilitate the method of PCR (Polymerase Chain Response) (Kumar, Singh & Sugimoto, 2020). PCR is a method utilized in molecular biology that amplifies a single or few copies of a particular DNA section (Kumar et al., 2020). This course of is achieved through the use of Taq Polymerase to create a number of copies of the goal DNA, permitting for the correct and fast evaluation of genetic materials (Larimore et al., 2019). This course of is utilized in a wide range of fields, from the prognosis of genetic illnesses to the identification of pathogens in medical settings (Kumar et al., 2020).

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